And the winner is…
221 N. Main St.Greenville, SC 29601
Grille 33s menu boasts a dozen burgers, each named after streets in downtown Greenville. From The Augusta, served with jalapeo pepper jack cheese, avocado and cilantro mayo, to The Poinsett, which sports a fried egg and bacon on top along with cheddar cheese, these are not your everyday burgers. Look for The Stone, which is served on a doughnut.
2541 N. PleasantburgGreenville, SC 29609
Mojo's is the defending Upstate Best Burger champion. This burger place prides itself on delivering "not just another burger"they specialize in using unique ingredients like teriyaki sauce and onion rings on their patties. They also serve baskets of fries or onion rings big enough to kayak down a river. Up for a challenge? Mojo's has several Man vs. Food-style burger challenges. Metromix readers voted Mojo's Best Burger 2011.
941 S. Main St.Greenville, SC 29601
Neighborhood: West End
Liberty Tap Room's burgers board features burgers made with Angus beef. There's a classic burger with lettuce and tomato or burgers a little more adventurous like the Freedom Burger served with cheddar, bacon, a fried egg, lettuce and tomato. There's also the Red, White and Bleu, which is dusted with Cajun-style spices, bleu cheese crumbles, bleu cheese dressing and onion straws. Metromix readers voted Liberty Tap Room for Best Burger 2010; they were also nominated for Best Guys Night Out Bar 2011.
404 Pendleton RoadClemson, SC 29631
This burger joint, a true Clemson classic icon, is ideal for anyone's meaty craving. Acting as one of Clemson's most loveable dives, Mac's Drive-In also offers milkshakes and soda. Located away from town but worth the drive. Metromix readers voted Mac's Drive In Best Restaurant in Clemson 2010 and 2011.
608-B S. Main St.Greenville, SC 29601
Neighborhood: West End
Chicora Alley's menu features a wide variety of dishes from tacos to pork medallions. But their lineup of burgers gets lots of points for originality. Their regular ol' burger is served with pico de gallo and guacamole. And then we get to specialty burgers like the Mideast Burger, which is served on pita bread. It's Angus beef topped with black bean and red pepper hummus, pico, cucumbers and a spicy sriracha/ranch sauce.
Last year's winner
711 SE Main St.Simpsonville, SC 29681
This burger place prides itself on delivering "not just another burger." They specialize in using unique ingredients like teriyaki sauce and onion rings. They also feature a wide range of sides, including french fries and fried pickles.